Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

To gain insight into the regulation of pancreatic beta-cell mitochondrial metabolism, the direct effects on respiration of different mitochondrial substrates, variations in the ATP/ADP ratio and free Ca2+ were examined using isolated mitochondria and permeabilized clonal pancreatic beta-cells (HIT)....

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Main Authors: Civelek, V N, Deeney, J T, Shalosky, N J, Tornheim, K, Hansford, R G, Prentki, M, Corkey, B E
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217665/
https://ncbi.nlm.nih.gov/pubmed/8809055
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