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Determination of the primary target for isoniazid in mycobacterial mycolic acid biosynthesis with Mycobacterium aurum A+.

The target of the potent antituberculosis drug isoniazid was investigated in Mycobacterium aurum A+, against which isoniazid has an MIC (the minimum concentration required to give growth inhibition) of 0.3 microgram/ml. Mycolic acid biosynthesis, measured by the incorporation of label from [1-14C]ac...

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Bibliografske podrobnosti
Main Authors: Wheeler, P R, Anderson, P M
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217642/
https://ncbi.nlm.nih.gov/pubmed/8809032
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