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Overexpression of human glucocerebrosidase containing different-sized leaders.

Gaucher disease results from impaired activity of the lysosomal enzyme glucocerebrosidase. Aiming at overexpressing the human glucocerebrosidase and testing the efficiency of the two in-frame ATGs of its gene in directing synthesis of an active enzyme, it was coupled to the T7 RNA polymerase promote...

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Hlavní autoři: Pasmanik-Chor, M, Elroy-Stein, O, Aerts, H, Agmon, V, Gatt, S, Horowitz, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217489/
https://ncbi.nlm.nih.gov/pubmed/8694790
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