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Modulation of the higher-order folding of chromatin by deletion of histone H3 and H4 terminal domains.

The 'tails' of histones H3 and H4 were removed by light in situ trypsin digestion of the nuclei. The alterations in the higher-order folding of chromatin resulting from this treatment were monitored by ethidium bromide titration. We found that DNA-intercalation of ethidium bromide under th...

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Autors principals: Krajewski, W A, Ausió, J
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217363/
https://ncbi.nlm.nih.gov/pubmed/8687379
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