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Modulation of the higher-order folding of chromatin by deletion of histone H3 and H4 terminal domains.

The 'tails' of histones H3 and H4 were removed by light in situ trypsin digestion of the nuclei. The alterations in the higher-order folding of chromatin resulting from this treatment were monitored by ethidium bromide titration. We found that DNA-intercalation of ethidium bromide under th...

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Main Authors: Krajewski, W A, Ausió, J
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217363/
https://ncbi.nlm.nih.gov/pubmed/8687379
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