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Dye-affinity labelling of bovine heart mitochondrial malate dehydrogenase and study of the NADH-binding site.

The ability of the reactive dichlorotriazine dye Vilmafix Blue A-R (VBAR) to act as an affinity label for bovine heart L-malate dehydrogenase (MDH) was studied. VBAR binds specifically and irreversibly to MDH (k3 0.16 min-1; KD 14.4 microM). The inactivation of the NADH-dependent enzyme by VBAR is c...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Labrou, N E, Eliopoulos, E, Clonis, Y D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217251/
https://ncbi.nlm.nih.gov/pubmed/8615848
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