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Interaction of mutants of tissue-type plasminogen activator with liver cells: effect of domain deletions.

The fibrin-specific thrombolyticum tissue-type plasminogen activator (t-PA) has proven to be a potent drug in several clinical trials, but its clinical application is complicated by the rapid clearance of t-PA from the circulation. The rapid plasma clearance of t-PA results from the uptake of t-PA i...

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Detalhes bibliográficos
Main Authors: Kuiper, J, Van't Hof, A, Otter, M, Biessen, E A, Rijken, D C, van Berkel, T J
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1216977/
https://ncbi.nlm.nih.gov/pubmed/8611154
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