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RNase III cleavage demonstrates a long range RNA: RNA duplex element flanking the hepatitis C virus internal ribosome entry site

Here, we show that Escherichia coli Ribonuclease III cleaves specifically the RNA genome of hepatitis C virus (HCV) within the first 570 nt with similar efficiency within two sequences which are ∼400 bases apart in the linear HCV map. Demonstrations include determination of the specificity of the cl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Beguiristain, Nerea, Robertson, Hugh D., Gómez, Jordi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1216335/
https://ncbi.nlm.nih.gov/pubmed/16170153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki822
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