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RNase II is important for A-site mRNA cleavage during ribosome pausing

In Escherichia coli, translational arrest can elicit cleavage of codons within the ribosomal A site. This A-site mRNA cleavage is independent of RelE, and has been proposed to be an endonucleolytic activity of the ribosome. Here, we show that the 3′→5′ exonuclease RNase II plays an important role in...

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Détails bibliographiques
Auteurs principaux: Garza-Sánchez, Fernando, Shoji, Shinichiro, Fredrick, Kurt, Hayes, Christopher S.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753246/
https://ncbi.nlm.nih.gov/pubmed/19627501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2009.06813.x
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