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Human Matrix Attachment Regions Insulate Transgene Expression from Chromosomal Position Effects in Drosophila melanogaster

Germ line transformation of white(−) Drosophila embryos with P-element vectors containing white expression cassettes results in flies with different eye color phenotypes due to position effects at the sites of transgene insertion. These position effects can be cured by specific DNA elements, such as...

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Bibliografiske detaljer
Main Authors: Namciu, Stephanie J., Blochlinger, Karen B., Fournier, R. E. K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC121496/
https://ncbi.nlm.nih.gov/pubmed/9528807
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