Human Matrix Attachment Regions Insulate Transgene Expression from Chromosomal Position Effects in Drosophila melanogaster

Germ line transformation of white(−) Drosophila embryos with P-element vectors containing white expression cassettes results in flies with different eye color phenotypes due to position effects at the sites of transgene insertion. These position effects can be cured by specific DNA elements, such as...

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Bibliographic Details
Main Authors: Namciu, Stephanie J., Blochlinger, Karen B., Fournier, R. E. K.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC121496/
https://ncbi.nlm.nih.gov/pubmed/9528807
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