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DNA Supercoiling Factor Localizes to Puffs on Polytene Chromosomes in Drosophila melanogaster

DNA supercoiling factor (SCF) was first identified in silkworm as a protein that generates negative supercoils in DNA in conjunction with eukaryotic topoisomerase II. To analyze the in vivo role of the factor, we cloned a cDNA encoding Drosophila melanogaster SCF. Northern analysis revealed 1.6- and...

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Detalhes bibliográficos
Main Authors: Kobayashi, Masatomo, Aita, Noriko, Hayashi, Shigeo, Okada, Kohichi, Ohta, Tsutomu, Hirose, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC109257/
https://ncbi.nlm.nih.gov/pubmed/9774687
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