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A Novel mre11 Mutation Impairs Processing of Double-Strand Breaks of DNA during Both Mitosis and Meiosis

Using complementation tests and nucleotide sequencing, we showed that the rad58-4 mutation was an allele of the MRE11 gene and have renamed the mutation mre11-58. Two amino acid changes from the wild-type sequence were identified; one is located at a conserved site of a phosphodiesterase motif, and...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Tsubouchi, Hideo, Ogawa, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121488/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.260
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