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A Novel mre11 Mutation Impairs Processing of Double-Strand Breaks of DNA during Both Mitosis and Meiosis

Using complementation tests and nucleotide sequencing, we showed that the rad58-4 mutation was an allele of the MRE11 gene and have renamed the mutation mre11-58. Two amino acid changes from the wild-type sequence were identified; one is located at a conserved site of a phosphodiesterase motif, and...

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Detaylı Bibliyografya
Asıl Yazarlar: Tsubouchi, Hideo, Ogawa, Hideyuki
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC121488/
https://ncbi.nlm.nih.gov/pubmed/9418873
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