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Improvement of the Fatty Acid Composition of an Oil-Producing Filamentous Fungus, Mortierella alpina 1S-4, through RNA Interference with Δ12-Desaturase Gene Expression

An oleaginous fungus, Mortierella alpina 1S-4, is used commercially for arachidonic acid production. Δ12-Desaturase, which desaturates oleic acid (18:1n-9) to linoleic acid (18:2n-6), is a key enzyme in the arachidonic acid biosynthetic pathway. To determine if RNA interference (RNAi) by double-stra...

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書誌詳細
主要な著者: Takeno, Seiki, Sakuradani, Eiji, Tomi, Akiko, Inohara-Ochiai, Misa, Kawashima, Hiroshi, Ashikari, Toshihiko, Shimizu, Sakayu
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1214649/
https://ncbi.nlm.nih.gov/pubmed/16151095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.9.5124-5128.2005
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