Protein Kinase B Activation and Lamellipodium Formation Are Independent Phosphoinositide 3-Kinase-Mediated Events Differentially Regulated by Endogenous Ras

Regulation of phosphoinositide 3-kinase (PI 3-kinase) can occur by binding of the regulatory p85 subunit to tyrosine-phosphorylated proteins and by binding of the p110 catalytic subunit to activated Ras. However, the way in which these regulatory mechanisms act to regulate PI 3-kinase in vivo is unc...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	van Weering, David H. J., de Rooij, Johan, Marte, Barbara, Downward, Julian, Bos, Johannes L., Burgering, Boudewijn M. T.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121410/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.1802
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