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Induction of Thioguanine- and Ouabain-Resistant Mutants and Single-Strand Breaks in the DNA of Chinese Hamster Ovary Cells by (3)H-Thymidine

Cultured Chinese hamster cells were labeled with 6-(3)H-thymidine or 5-methyl-(3)H-thymidine and allowed to accumulate damage from ( 3)H decays for various periods of time while frozen. The frequencies of cells resistant to 6-thioguanine or ouabain and the amount of DNA damage (i.e., number of singl...

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Autor principal: Cleaver, James E.
Format: Artigo
Idioma:Inglês
Publicat: 1977
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1213721/
https://ncbi.nlm.nih.gov/pubmed/914028
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