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Bromodeoxyuridine-Induced Mutations in Synchronous Chinese Hamster Cells: Temporal Induction of 6-Thioguanine and Ouabain Resistance during DNA Replication

Mutations were induced in synchronous Chinese hamster cells by bromodeoxyuridine (BUdR) incorporated into cells for one-hour periods in the cell cycle. There was a very pronounced temporal dependence during the first half of the DNA synthesis period for the induction of damage leading to 6-thioguani...

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Detalhes bibliográficos
Main Authors: Burki, H. John, Aebersold, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1213891/
https://ncbi.nlm.nih.gov/pubmed/730050
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