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Uranyl Acetate Induced DNA Single Strand Breaks and AP Sites in Chinese Hamster Ovary Cells

The aim of this study is to characterize the genotoxicity of depleted uranium (DU) in Chinese Hamster Ovary cells (CHO) with mutations in various DNA repair pathways. CHO cells were exposed to 0 – 300 μM of soluble DU as uranyl acetate (UA) for 0 – 48 hr. Intracellular UA concentrations were measure...

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Bibliografiske detaljer
Udgivet i:Toxicol Appl Pharmacol
Main Authors: Yellowhair, Monica, Romanotto, Michelle R., Stearns, Diane M., Lantz, R. Clark
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972677/
https://ncbi.nlm.nih.gov/pubmed/29698738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.04.022
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