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Genetic and Environmental Factors Affecting the De Novo Appearance of the [Psi(+)] Prion in Saccharomyces Cerevisiae

It has previously been shown that yeast prion [PSI(+)] is cured by GuHCl, although reports on reversibility of curing were contradictory. Here we show that GuHCl treatment of both [PSI(+)] and [psi(-)] yeast strains results in two classes of [psi(-)] derivatives: Pin(+), in which [PSI(+)] can be rei...

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Autori principali: Derkatch, I. L., Bradley, M. E., Zhou, P., Chernoff, Y. O., Liebman, S. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1208174/
https://ncbi.nlm.nih.gov/pubmed/9335589
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