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The Vacuolar Atpase of Neurospora Crassa Is Indispensable: Inactivation of the Vma-1 Gene by Repeat-Induced Point Mutation

To analyze the phenotype of cells lacking the vacuolar ATPase, we inactivated the vma-1 gene, which encodes the catalytic subunit of the enzyme. Because preliminary experiments suggested the vma-1 gene was essential, we developed a method of simultaneously inactivating the gene and complementing it...

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Detalhes bibliográficos
Main Authors: Ferea, T. L., Bowman, B. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1207248/
https://ncbi.nlm.nih.gov/pubmed/8722770
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