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Plasmid-Mediated Induction of Recombination in Yeast

Diploid yeast cells heteroallelic at the HIS3 locus were transformed with a minichromosome (centromeric plasmid) carrying homology to the HIS3 region and containing the same two mutations as were present in the chromosomes. When a double-strand break (DSB) was introduced in the region of homology, a...

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Bibliographic Details
Main Authors: Silberman, R., Kupiec, M.
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1205951/
https://ncbi.nlm.nih.gov/pubmed/8056321
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