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Spontaneous Mutation at a 5-Methylcytosine Hotspot Is Prevented by Very Short Patch (Vsp) Mismatch Repair
In many strains of Escherichia coli, the product of gene dcm methylates the internal cytosines in the sequence 5'CC(A or T)GG. Spontaneous deamination of 5-methylcytosine produces thymine which, if not corrected, can result in a transition mutation. 5-Methylcytosines in the lacI gene are hotspo...
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
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1991
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1204449/ https://ncbi.nlm.nih.gov/pubmed/1829427 |
| Etiketak: |
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