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Mutation Rates, Spectra and Hotspots in Mismatch Repair-Deficient Caenorhabditis elegans

Although it is clear that postreplicative DNA mismatch repair (MMR) plays a critical role in maintaining genomic stability in nearly all forms of life surveyed, much remains to be understood about the genome-wide impact of MMR on spontaneous mutation processes and the extent to which MMR-deficient m...

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Bibliografske podrobnosti
Main Authors: Denver, Dee R., Feinberg, Seth, Estes, Suzanne, Thomas, W. Kelley, Lynch, Michael
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449714/
https://ncbi.nlm.nih.gov/pubmed/15716493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.038521
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