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Mechanisms of Spontaneous and Induced Frameshift Mutation in Bacteriophage T4

Frequencies of spontaneous and proflavine-induced frameshift mutations increase dramatically as a function of the number of reiterated base pairs at each of two sites in the lysozyme gene of bacteriophage T4. At each site, proflavine induces addition mutations more frequently than deletion mutations...

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Detalhes bibliográficos
Main Authors: Streisinger, George, Owen, Joyce Emrich
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1202499/
https://ncbi.nlm.nih.gov/pubmed/3988038
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