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Mechanisms of Spontaneous and Induced Frameshift Mutation in Bacteriophage T4

Frequencies of spontaneous and proflavine-induced frameshift mutations increase dramatically as a function of the number of reiterated base pairs at each of two sites in the lysozyme gene of bacteriophage T4. At each site, proflavine induces addition mutations more frequently than deletion mutations...

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Bibliographic Details
Main Authors: Streisinger, George, Owen, Joyce Emrich
Format: Artigo
Language:Inglês
Published: 1985
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1202499/
https://ncbi.nlm.nih.gov/pubmed/3988038
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