Deviations from Hardy-Weinberg Proportions: Sampling Variances and Use in Estimation of Inbreeding Coefficients

An analysis is made of the distribution of deviations from Hardy-Weinberg proportions with k alleles and of estimates of inbreeding coefficients (f) obtained from these deviations.—If f is small, the best estimate of f in large samples is shown to be 2Σ( i)(T(ii)/N(i))/(k - 1), where T(ii) is an unb...

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Bibliographic Details
Main Authors: Robertson, Alan, Hill, William G.
Format: Artigo
Language:Inglês
Published: 1984
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1202385/
https://ncbi.nlm.nih.gov/pubmed/6745643
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