The potential role of amyloid β in the pathogenesis of age-related macular degeneration

Drusen are extracellular deposits that lie beneath the retinal pigment epithelium (RPE) and are the earliest signs of age-related macular degeneration (AMD). Recent proteome analysis demonstrated that amyloid β (Aβ) deposition was specific to drusen from eyes with AMD. To work toward a molecular und...

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Main Authors: Yoshida, Takeshi, Ohno-Matsui, Kyoko, Ichinose, Shizuko, Sato, Tetsuji, Iwata, Nobuhisa, Saido, Takaomi C., Hisatomi, Toshio, Mochizuki, Manabu, Morita, Ikuo
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2005
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201663/
https://ncbi.nlm.nih.gov/pubmed/16167083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24635
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