Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells

Bruton's tyrosine kinase (BTK) deficiency results in a differentiation block at the pre-B cell stage. Likewise, acute lymphoblastic leukemia cells are typically arrested at early stages of B cell development. We therefore investigated BTK function in B cell precursor leukemia cells carrying a B...

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Detalhes bibliográficos
Main Authors: Feldhahn, Niklas, Río, Paula, Soh, Bonaventure Ndikung Bejeng, Liedtke, Stefanie, Sprangers, Mieke, Klein, Florian, Wernet, Peter, Jumaa, Hassan, Hofmann, Wolf-Karsten, Hanenberg, Helmut, Rowley, Janet D., Müschen, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201599/
https://ncbi.nlm.nih.gov/pubmed/16141323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505196102
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