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Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch
Specific recognition of phosphatidylinositol 3-phosphate [PtdIns(3)P] by the FYVE domain targets cytosolic proteins to endosomal membranes during key signaling and trafficking events within eukaryotic cells. Here, we show that this membrane targeting is regulated by the acidic cellular environment....
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201587/ https://ncbi.nlm.nih.gov/pubmed/16141328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503900102 |
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