Targeting of the FYVE domain to endosomal membranes is regulated by a histidine switch

Specific recognition of phosphatidylinositol 3-phosphate [PtdIns(3)P] by the FYVE domain targets cytosolic proteins to endosomal membranes during key signaling and trafficking events within eukaryotic cells. Here, we show that this membrane targeting is regulated by the acidic cellular environment....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lee, Stephanie A., Eyeson, Rosemary, Cheever, Matthew L., Geng, Jinming, Verkhusha, Vladislav V., Burd, Christopher, Overduin, Michael, Kutateladze, Tatiana G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201587/
https://ncbi.nlm.nih.gov/pubmed/16141328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503900102
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge