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Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1

Nitric oxide (NO) donors have been shown to stimulate and inhibit the proliferation, migration, and differentiation of endothelial cells in vitro and angiogenesis in vivo. Recently, we have shown distinct thresholds for NO to regulate p53-Ser-15P, phosphorylated extracellular signal-regulated kinase...

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Autors principals: Ridnour, Lisa A., Isenberg, Jeffrey S., Espey, Michael G., Thomas, Douglas D., Roberts, David D., Wink, David A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201580/
https://ncbi.nlm.nih.gov/pubmed/16141331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502979102
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