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Upregulation of GRP78 and antiapoptotic signaling in murine peritoneal macrophages exposed to insulin
The unfolded protein response pathway (UPR) compensates for excessive protein accumulation in the ER. Since insulin, induces global protein synthesis, it may cause accumulation of unfolded proteins in the ER, thus triggering UPR. We assessed UPR activation in insulin-treated murine peritoneal macrop...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201561/ https://ncbi.nlm.nih.gov/pubmed/15845644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1104685 |
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