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Identification of an Acquired JAK2 Mutation in Polycythemia Vera

Polycythemia vera (PV) is a human clonal hematological disorder. The molecular etiology of the disease has not been identified. PV hematopoietic progenitor cells exhibit hypersensitivity to growth factors and cytokines, suggesting possible abnormalities in protein tyrosine kinases and phosphatases....

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Detalhes bibliográficos
Main Authors: Zhao, Runxiang, Xing, Shu, Li, Zhe, Fu, Xueqi, Li, Qingshan, Krantz, Sanford B., Zhao, Zhizhuang Joe
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201515/
https://ncbi.nlm.nih.gov/pubmed/15863514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C500138200
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