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Preservation of Eumelanin Hair Pigmentation in Proopiomelanocortin-Deficient Mice on a Nonagouti (a/a) Genetic Background
The original strain of proopiomelanocortin (POMC)-deficient mice (Pomc(−/−) ) was generated by homologous recombination in 129X1/SvJ (A(w)/A(w))-derived embryonic stem cells using a targeting construct that deleted exon 3, encoding all the known functional POMC-derived peptides including αMSH, from...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201461/ https://ncbi.nlm.nih.gov/pubmed/15564334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2004-0733 |
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