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Endogenous Activation of Metabotropic Glutamate Receptors Modulates GABAergic Transmission to Gonadotropin-Releasing Hormone Neurons and Alters Their Firing Rate: A Possible Local Feedback Circuit

Gonadotropin-releasing hormone (GnRH) neurons are the primary central regulators of fertility, receiving input from GABAergic afferents via GABA(A) receptors. We tested whether metabotropic glutamate receptors (mGluRs) regulate GABA transmission to GnRH neurons and GnRH neuronal firing pattern. Whol...

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Autors principals: Chu, Zhiguo, Moenter, Suzanne M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201448/
https://ncbi.nlm.nih.gov/pubmed/15958740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0913-05.2005
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