Hyperpolarization-Activated Currents in Gonadotropin-Releasing Hormone (GnRH) Neurons Contribute to Intrinsic Excitability and Are Regulated by Gonadal Steroid Feedback

Pulsatile release of gonadotropin-releasing hormone (GnRH) is required for fertility and is regulated by steroid feedback. Hyperpolarization-activated currents (I(h)) play a critical role in many rhythmic neurons. We examined the contribution of I(h) to the membrane and firing properties of GnRH neu...

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Bibliographic Details
Main Authors: Chu, Zhiguo, Takagi, Hiroshi, Moenter, Suzanne M.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2968704/
https://ncbi.nlm.nih.gov/pubmed/20926664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1687-10.2010
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