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Thermal difference spectra: a specific signature for nucleic acid structures

We show that nucleic acid structures may be conveniently and inexpensively characterized by their UV thermal difference spectra. A thermal difference spectrum (TDS) is obtained for a nucleic acid by simply recording the ultraviolet absorbance spectra of the unfolded and folded states at temperatures...

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Bibliografiske detaljer
Main Authors: Mergny, Jean-Louis, Li, Jing, Lacroix, Laurent, Amrane, Samir, Chaires, Jonathan B.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201377/
https://ncbi.nlm.nih.gov/pubmed/16157860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni134
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