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Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes

Evidence from inbred strains of mice indicates that a quarter or more of the mammalian genome consists of chromosome regions containing clusters of functionally related genes. The intense selection pressures during inbreeding favor the coinheritance of optimal sets of alleles among these genetically...

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Detalhes bibliográficos
Main Authors: Petkov, Petko M, Graber, Joel H, Churchill, Gary A, DiPetrillo, Keith, King, Benjamin L, Paigen, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201368/
https://ncbi.nlm.nih.gov/pubmed/16163395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010033
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