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Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes

Evidence from inbred strains of mice indicates that a quarter or more of the mammalian genome consists of chromosome regions containing clusters of functionally related genes. The intense selection pressures during inbreeding favor the coinheritance of optimal sets of alleles among these genetically...

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Autors principals: Petkov, Petko M, Graber, Joel H, Churchill, Gary A, DiPetrillo, Keith, King, Benjamin L, Paigen, Kenneth
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201368/
https://ncbi.nlm.nih.gov/pubmed/16163395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010033
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