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Acetylation of HIV-1 integrase by p300 regulates viral integration

Integration of HIV-1 into the human genome, which is catalyzed by the viral protein integrase (IN), preferentially occurs near transcriptionally active genes. Here we show that p300, a cellular acetyltransferase that regulates chromatin conformation through the acetylation of histones, also acetylat...

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Hlavní autoři: Cereseto, Anna, Manganaro, Lara, Gutierrez, Maria Ines, Terreni, Mariaelena, Fittipaldi, Antonio, Lusic, Marina, Marcello, Alessandro, Giacca, Mauro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201351/
https://ncbi.nlm.nih.gov/pubmed/16096645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600770
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