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Acetylation of HIV-1 integrase by p300 regulates viral integration
Integration of HIV-1 into the human genome, which is catalyzed by the viral protein integrase (IN), preferentially occurs near transcriptionally active genes. Here we show that p300, a cellular acetyltransferase that regulates chromatin conformation through the acetylation of histones, also acetylat...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201351/ https://ncbi.nlm.nih.gov/pubmed/16096645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600770 |
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