LcrV Plague Vaccine with Altered Immunomodulatory Properties

Yersinia pestis, the causative agent of plague, secretes LcrV (low-calcium-response V or V antigen) during infection. LcrV triggers the release of interleukin 10 (IL-10) by host immune cells and suppresses proinflammatory cytokines such as tumor necrosis factor alpha and gamma interferon as well as...

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Detalhes bibliográficos
Main Authors: Overheim, Katie A., DePaolo, R. William, DeBord, Kristin L., Morrin, Elizabeth M., Anderson, Debra M., Green, Nathaniel M., Brubaker, Robert R., Jabri, Bana, Schneewind, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201268/
https://ncbi.nlm.nih.gov/pubmed/16041032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5152-5159.2005
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