Factors Associated with Severe Granulomatous Pneumonia in Mycobacterium tuberculosis-Infected Mice Vaccinated Therapeutically with hsp65 DNA

Resistant C57BL/6 mice infected in the lungs with Mycobacterium tuberculosis and then therapeutically vaccinated with Mycobacterium leprae-derived hsp65 DNA develop severe granulomatous pneumonia and tissue damage. Analysis of cells accumulating in the lungs of these animals revealed substantial inc...

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Main Authors: Taylor, Jennifer L., Ordway, Diane J., Troudt, JoLynn, Gonzalez-Juarrero, Mercedes, Basaraba, Randall J., Orme, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201265/
https://ncbi.nlm.nih.gov/pubmed/16041037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5189-5193.2005
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