Identification and Characterization of Protective T Cells in hsp65 DNA-Vaccinated and Mycobacterium tuberculosis-Infected Mice

Immunization by intramuscular injection of plasmid DNA expressing mycobacterial 65-kDa heat shock protein (hsp65) protects mice against challenge with virulent Mycobacterium tuberculosis H37Rv. During infection or after immunization, CD4(+)/CD8(−) and CD8(+)/CD4(−) hsp65-reactive T cells increased e...

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Bibliographische Detailangaben
Hauptverfasser: Bonato, Vania L. D., Lima, Valeria M. F., Tascon, Ricardo E., Lowrie, Douglas B., Silva, Celio L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC107873/
https://ncbi.nlm.nih.gov/pubmed/9423854
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