Identification and Characterization of Protective T Cells in hsp65 DNA-Vaccinated and Mycobacterium tuberculosis-Infected Mice

Immunization by intramuscular injection of plasmid DNA expressing mycobacterial 65-kDa heat shock protein (hsp65) protects mice against challenge with virulent Mycobacterium tuberculosis H37Rv. During infection or after immunization, CD4(+)/CD8(−) and CD8(+)/CD4(−) hsp65-reactive T cells increased e...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Bonato, Vania L. D., Lima, Valeria M. F., Tascon, Ricardo E., Lowrie, Douglas B., Silva, Celio L.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1998
Subjects:	Microbial Immunity and Vaccines
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9423854/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.1.169-175.1998
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