Protection by Natural Human Immunoglobulin M Antibody to Meningococcal Serogroup B Capsular Polysaccharide in the Infant Rat Protection Assay Is Independent of Complement-Mediated Bacterial Lysis

Neisseria meningitidis, an important cause of bacterial meningitis and septicemia worldwide, is associated with high mortality and serious sequelae. Natural immunity against meningococcal disease develops with age, but the specificity and functional activity of natural antibodies associated with pro...

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Main Authors: Toropainen, Maija, Saarinen, Leena, Wedege, Elisabeth, Bolstad, Karin, Michaelsen, Terje E., Aase, Audun, Käyhty, Helena
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201264/
https://ncbi.nlm.nih.gov/pubmed/16040982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4694-4703.2005
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