Bacterial Ghosts as an Oral Vaccine: a Single Dose of Escherichia coli O157:H7 Bacterial Ghosts Protects Mice against Lethal Challenge

Enterohemorrhagic Escherichia coli (EHEC) is a bacterial pathogen that is associated with several life-threatening diseases for humans. The combination of protein E-mediated cell lysis to produce EHEC ghosts and staphylococcal nuclease A to degrade DNA was used for the development of an oral EHEC va...

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Detalhes bibliográficos
Main Authors: Mayr, Ulrike Beate, Haller, Christoph, Haidinger, Wolfgang, Atrasheuskaya, Alena, Bukin, Eugenij, Lubitz, Werner, Ignatyev, Georgy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201255/
https://ncbi.nlm.nih.gov/pubmed/16040994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.4810-4817.2005
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