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Prolonged Survival of a Murine Model of Cerebral Malaria by Kynurenine Pathway Inhibition
C57BL/6J mice infected with Plasmodium berghei ANKA develop neurological dysfunction and die within 7 days of infection. We show that treatment of infected mice with a kynurenine-3-hydroxylase inhibitor prevents them from developing neurological symptoms and extends their life span threefold until s...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201246/ https://ncbi.nlm.nih.gov/pubmed/16041050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.8.5249-5251.2005 |
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