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Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket
Apical membrane antigen 1 (AMA1) is a leading malaria vaccine candidate that possesses polymorphisms that may pose a problem for a vaccine based on this antigen. Knowledge of the distribution of the polymorphic sites on the surface of AMA1 is necessary to obtain a detailed understanding of their sig...
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Autori principali: | , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
National Academy of Sciences
2005
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1200259/ https://ncbi.nlm.nih.gov/pubmed/16129835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501808102 |
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