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Geographical Structure of Diversity and Differences between Symptomatic and Asymptomatic Infections for Plasmodium falciparum Vaccine Candidate AMA1

Plasmodium falciparum apical membrane antigen 1 (AMA1) is a prime malaria vaccine candidate. Antigenic diversity within parasite populations is one of the main factors potentially limiting the efficacy of any asexual-stage vaccine, including one based on AMA1. The DNA coding for the most variable re...

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Detalhes bibliográficos
Main Authors: Cortés, Alfred, Mellombo, Mata, Mueller, Ivo, Benet, Ariadna, Reeder, John C., Anders, Robin F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148836/
https://ncbi.nlm.nih.gov/pubmed/12595459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1416-1426.2003
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