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Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket

Apical membrane antigen 1 (AMA1) is a leading malaria vaccine candidate that possesses polymorphisms that may pose a problem for a vaccine based on this antigen. Knowledge of the distribution of the polymorphic sites on the surface of AMA1 is necessary to obtain a detailed understanding of their sig...

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Detalhes bibliográficos
Main Authors: Bai, Tao, Becker, Michael, Gupta, Aditi, Strike, Phillip, Murphy, Vince J., Anders, Robin F., Batchelor, Adrian H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1200259/
https://ncbi.nlm.nih.gov/pubmed/16129835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501808102
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