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Absence of pathogenic mitochondrial DNA mutations in mouse brain tumors

BACKGROUND: Somatic mutations in the mitochondrial genome occur in numerous tumor types including brain tumors. These mutations are generally found in the hypervariable regions I and II of the displacement loop and unlikely alter mitochondrial function. Two hypervariable regions of mononucleotide re...

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Detalhes bibliográficos
Main Authors: Kiebish, Michael A, Seyfried, Thomas N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199588/
https://ncbi.nlm.nih.gov/pubmed/16105171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-5-102
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